Round 299

Round UUID: 22c40596-0196-4602-ae03-d277ba7a37e6

Prompt:

You are given one entity at a time with the following fields.
• Histogen_Complex  (string)
• Sex               ("male" or "female")
• Treatment_Months  (number – can be decimal)
• Genetic_Class_A_Matches (integer ≥ 0)
• Genetic_Class_B_Matches (integer ≥ 0)
• TcQ_mass          (number – can be decimal)
• Cohort            (string)

Predict the treatment OUTCOME for that entity.
Only two outcomes are possible:
  Success
  Failure

Apply the rules BELOW IN THE EXACT ORDER.  As soon as one rule is satisfied, output its outcome and STOP – do not check any lower-priority rules.  The rules are mutually exclusive and collectively exhaustive, so they cover every possible row.

Let total_matches = Genetic_Class_A_Matches + Genetic_Class_B_Matches.

RULE 1   HIGH GENETIC BURDEN → Failure
    If total_matches ≥ 6 → Failure

RULE 2   FEMALE, BETA VARIANT & VERY-LONG TREATMENT → Failure
    If Sex = female AND Histogen_Complex = Beta AND Treatment_Months ≥ 100 → Failure

RULE 3   FEMALE, BETA VARIANT & EXTREME MASS → Failure
    If Sex = female AND Histogen_Complex = Beta AND TcQ_mass > 200000 → Failure

RULE 4   MALE, DELTA VARIANT WITH MANY MUTATIONS & <50 k MASS → Failure
    If Sex = male AND Histogen_Complex = Delta AND total_matches ≥ 3 AND TcQ_mass < 50000 → Failure

RULE 5   MALE, HIGH MUTATION COUNT & LOW MASS → Failure
    If Sex = male AND total_matches ≥ 4 AND TcQ_mass < 30000 AND Treatment_Months < 90 → Failure

RULE 6   EXTREME TcQ_mass (any sex) → Success
    If TcQ_mass > 200000 → Success

RULE 7   SHORT TREATMENT WINDOW FOR FEMALES → Success
    If Sex = female AND Treatment_Months < 24 → Success

RULE 8   FEMALE, BETA VARIANT – HIGH MASS, LOW MUTATIONS, MODERATE DURATION → Success
    If Sex = female AND Histogen_Complex = Beta AND 25000 ≤ TcQ_mass ≤ 200000 AND Treatment_Months < 80 AND total_matches ≤ 2 → Success

RULE 9   FEMALE, BETA VARIANT – MID MASS, LOW MUTATIONS, LONGER DURATION → Success
    If Sex = female AND Histogen_Complex = Beta AND 25000 ≤ TcQ_mass ≤ 60000 AND 100 ≤ Treatment_Months ≤ 140 AND total_matches ≤ 2 → Success

RULE 10  MALE DEFAULT → Success
    If Sex = male → Success

RULE 11  OTHERWISE → Failure
    (All remaining cases) → Failure

Output exactly one word – either Success or Failure – and nothing else.