Round 353

Round UUID: 45987b58-97c6-476e-ab87-0baa46d1b3cc

Prompt:

### Revised Prediction Rules for Entity Classification ###

Refine the following decision rules to predict Failure or Success accurately, targeting edge cases and ambiguity:

1. General Threshold Rules:
   - Predict Failure if `TcQ_mass` > 50,000 and `Treatment_Months` < 130, unless explicitly overridden by Genetic_Class or cohort-specific conditions.
   - Predict Success only if `TcQ_mass` > 50,000, `Treatment_Months` >= 130, and `Genetic_Class_A_Matches` >= 3 and `Genetic_Class_B_Matches` >= 3.

2. Rules for `Histogen_Complex` = 'Beta':
   - Predict Failure if `Genetic_Class_A_Matches` + `Genetic_Class_B_Matches` < 6, regardless of other factors.
   - Predict Failure if `TcQ_mass` > 50,000 and any Genetic_Class threshold (<3) fails.
   - Prioritize Success only if all thresholds are met: `TcQ_mass` > 50,000, `Treatment_Months` > 130, and each Genetic_Class reaches at least 3.

3. Rules for `Histogen_Complex` = 'Delta' or 'Omicron':
   - Predict Failure if `TcQ_mass` > 25,000 and `Genetic_Class_A_Matches` or `Genetic_Class_B_Matches` < 3.
   - Predict Failure for `Treatment_Months` < 60 when combined Genetic Class matches are below 6.
   - For `TcQ_mass` in the range 20,000-25,000:
     a. Predict Success if `Treatment_Months` >= 100 and each Genetic_Class >= 3.
     b. Otherwise, predict Failure.
   - Automatically predict Failure if combined Genetic Class score is 4 or below, unless cohort-specific rules apply.

4. Specific Rules for Cohorts:
   - Predict Success for cohort='Delhi' if `TcQ_mass` > 200,000, regardless of Genetic_Class. Otherwise, predict Failure.
   - Other cohorts adhere strictly to thresholds for Genetic_Class matches, with no override for high `TcQ_mass` unless `Treatment_Months` > 130.

5. Gender-Specific Rules (for Sex = female):
   - Predict Failure if `Treatment_Months` > 110, `TcQ_mass` is between 25,000-40,000, and either Genetic_Class threshold (<3) fails.
   - Predict Success only if `TcQ_mass` > 40,000 and combined Genetic_Class matches >= 7.

6. Special Override Rules:
   - Predict Failure universally if combined `Genetic_Class_A_Matches` + `Genetic_Class_B_Matches` < 4.
   - Predict Success universally if combined Genetic_Class matches >= 8 and `Treatment_Months` > 100, provided no critical TcQ_mass condition fails above 50,000.
   - For cases where `Histogen_Complex` = 'Omicron', override rules if `TcQ_mass` >= 35,000 and `Genetic_Class` conditions are not met.

7. Catch-All Rule:
   - Default to Failure if an entry does not decisively meet any outlined Success criteria or has borderline thresholds in ambiguity.