Round 351

Round UUID: 88db9a08-a368-4465-9a4e-4ee7925b294f

Prompt:

### Enhanced Decision Rules for Prediction ###

Use the following enhanced rules to predict Failure or Success based on the entity data:

1. If `Histogen_Complex` is 'Beta':
   - Predict Failure if `TcQ_mass` > 50,000 and `Treatment_Months` < 130. 
   - Predict Success if `TcQ_mass` > 50,000, `Treatment_Months` >= 130, and both `Genetic_Class_A_Matches` >= 3 and `Genetic_Class_B_Matches` >= 3.
   - Override to Failure if either `Genetic_Class_A_Matches` < 3 or `Genetic_Class_B_Matches` < 3, regardless of other parameters, unless explicit cohort-specific exceptions apply.

2. If `Histogen_Complex` is 'Delta' or 'Omicron':
   - Predict Success if `Genetic_Class_A_Matches` >= 3, `Genetic_Class_B_Matches` >= 3, `TcQ_mass` > 20,000, and `Treatment_Months` >= 110.
   - Predict Failure if `TcQ_mass` >= 25,000 and either `Genetic_Class_A_Matches` < 3 or `Genetic_Class_B_Matches` < 3 or if `Treatment_Months` is < 90.
   - If `TcQ_mass` is between 20,000 and 25,000:
     a. Predict Success if `Treatment_Months` >= 130 and both Genetic_Class thresholds (>=3) are met.
     b. Predict Failure if either `Treatment_Months` < 130 or Genetic_Class thresholds are not met.

3. For cohort = 'Delhi':
   - Predict Success if `TcQ_mass` > 200,000 regardless of other parameters.
   - Predict Failure if `TcQ_mass` <= 200,000, or either `Genetic_Class_A_Matches` < 3, or `Treatment_Months` < 60.

4. If `Sex` is 'female':
   - Predict Failure if `Treatment_Months` > 110, `TcQ_mass` is between 25,000 and 40,000, and either `Genetic_Class_A_Matches` or `Genetic_Class_B_Matches` < 3.
   - Predict Success if `TcQ_mass` > 40,000 and both Genetic_Class matches are >= 4, unless overridden by the Histogen_Complex conditions (Rule 1 or 2).

5. Adjusted Override for Genetic Classes:
   - Automatically predict Failure if `Genetic_Class_A_Matches` < 2 or `Genetic_Class_B_Matches` < 2 unless overridden by Delhi cohort exceptions. Entries just meeting thresholds (e.g., `Genetic_Class_A_Matches` or `Genetic_Class_B_Matches` == 2) should be scrutinized under stricter conditions for `TcQ_mass` > 100,000 or when `Treatment_Months` is borderline for success conditions.

6. Catch-All Rule for Genetic Thresholds:
   - If `Genetic_Class_A_Matches` >= 4 and `Genetic_Class_B_Matches` >= 4:
     - Predict Success if `TcQ_mass` > 25,000 and `Treatment_Months` >= 100.
   - Predict Failure if any lower Genetic thresholds fail to sustain above criteria and align (for `Histogens Beta, Delta`).

7. Special Override conditions:
   - If `Histogen_Complex` is 'Omicron' and `TcQ_mass` >= 35,000:
     a. Predict Failure if either Genetic_Class threshold fails, non-matching thresholds (e.g., A-matches). 
     b. Predict exclusively Success if enough Trait-Mines portions align nit suggest measurable indicators exceed > Conditioned Schema.sections,.Espc familial Risk markers calibrations-text.