Round UUID: 23995d10-9d6b-491b-8ac5-549c0ab5602e
Prompt:
### Optimized Decision Rules for Prediction ###
Use the following optimized rules to predict Failure or Success based on the entity data:
1. If `Histogen_Complex` is 'Beta':
- Predict Failure if `TcQ_mass` > 50,000 and `Treatment_Months` < 130.
- Predict Success if `TcQ_mass` > 50,000, `Treatment_Months` >= 130, and both `Genetic_Class_A_Matches` and `Genetic_Class_B_Matches` >= 3.
- Override to Failure if either `Genetic_Class_A_Matches` or `Genetic_Class_B_Matches` is < 3, regardless of the other parameters.
2. If `Histogen_Complex` is 'Delta' or 'Omicron':
- Predict Success if `Genetic_Class_A_Matches` >= 3, `Genetic_Class_B_Matches` >= 3, `TcQ_mass` > 20,000, and `Treatment_Months` >= 100.
- Predict Failure if `TcQ_mass` >= 25,000 and either `Genetic_Class_A_Matches` < 3 or `Genetic_Class_B_Matches` < 3.
- If `TcQ_mass` is between 20,000 and 25,000:
a. Predict Success if `Treatment_Months` >= 130 and both Genetic_Class thresholds (>=3) are met.
b. Predict Failure if either `Treatment_Months` < 130 or Genetic_Class thresholds are not met.
3. For cohort='Delhi':
- Predict Success if `TcQ_mass` > 200,000 regardless of other parameters.
- Predict Failure if `TcQ_mass` <= 200,000, `Genetic_Class_A_Matches` < 3, or `Treatment_Months` < 60.
4. If `Sex` is 'female':
- Predict Failure if `Treatment_Months` > 110, `TcQ_mass` is between 25,000 and 40,000, and either `Genetic_Class_A_Matches` or `Genetic_Class_B_Matches` < 3.
- Predict Success if `TcQ_mass` > 40,000 and both Genetic_Class matches are >= 3, unless overridden by the Histogen_Complex conditions (Rule 1 or 2).
5. If either `Genetic_Class_A_Matches` or `Genetic_Class_B_Matches` is < 3:
- Predict Failure regardless of other factors except for the 'Delhi' cohort-specific conditions.
6. For any entry where `Genetic_Class_A_Matches` >= 3 and `Genetic_Class_B_Matches` >= 3:
- Predict Success if `TcQ_mass` > 20,000, `Treatment_Months` >= 100, and `Histogen_Complex` is either 'Beta', 'Delta', or 'Omicron'.
7. Override conditions:
- If `Histogen_Complex` is 'Omicron' and `TcQ_mass` >= 30,000:
a. Predict Failure if either Genetic_Class threshold is missed or `Treatment_Months` < 110.
b. Predict Success only if both Genetic_Class thresholds (>=3) are met and `Treatment_Months` >= 110.
8. Default to Failure for all cases that do not meet the above criteria explicitly.
### Additional Notes ###
- Apply rules strictly in priority order as listed.
- Enhance conservatism for extreme cases (`TcQ_mass` >70,000); scrutinize without defaulting to Success unless explicitly covered.
- Address edge scenarios by transparently tightening criteria for Genetic_Class matches and adjusting Treatment thresholds for clarity.