Round 348

Round UUID: 3d8cd533-5b58-4fe0-8754-7bdffbff9255

Prompt:

### Revised Decision Rules for Prediction ###

Use the following updated rules to predict Failure or Success based on the entity data:

1. If `Histogen_Complex` is 'Beta':
   - Predict Failure if `TcQ_mass` > 50,000 and `Treatment_Months` < 120.
   - Predict Success if `TcQ_mass` > 50,000 and `Treatment_Months` >= 120 and both `Genetic_Class_A_Matches` and `Genetic_Class_B_Matches` >= 2.
   - Override to Failure if `Genetic_Class_A_Matches` or `Genetic_Class_B_Matches` < 2 regardless of `TcQ_mass`.

2. If `Histogen_Complex` is 'Delta' or 'Omicron':
   - Predict Success if `Genetic_Class_A_Matches` >= 2, `Genetic_Class_B_Matches` >= 2, `TcQ_mass` > 15,000, and `Treatment_Months` >= 80.
   - Predict Failure if `TcQ_mass` >= 25,000 and either `Genetic_Class_A_Matches` < 2 or `Genetic_Class_B_Matches` < 2.
   - If `TcQ_mass` is between 15,000 and 25,000:
     a. Predict Success if `Treatment_Months` >= 120 and both Genetic_Class thresholds are met.
     b. Predict Failure if `Treatment_Months` < 120 or either Genetic_Class threshold is missed.

3. For cohort='Delhi':
   - Predict Success if `TcQ_mass` > 200,000 regardless of other parameters.
   - Predict Failure if `TcQ_mass` <= 200,000 and (`Genetic_Class_A_Matches` < 2 or `Treatment_Months` < 50).

4. If `Sex` is 'female':
   - Predict Failure if `Treatment_Months` > 100, `TcQ_mass` is between 20,000 and 40,000 and `Genetic_Class_A_Matches` < 2 or `Genetic_Class_B_Matches` < 2.
   - Predict Success if `TcQ_mass` > 35,000 and both Genetic_Class matches are >= 2, unless overridden by Histogen conditions.

5. If either Genetic_Class_A_Matches or Genetic_Class_B_Matches is < 2:
   - Always predict Failure if this condition is met regardless of other factors except for the 'Delhi' cohort.

6. For any entry with `Genetic_Class_A_Matches` >= 2 and `Genetic_Class_B_Matches` >= 2:
   - Predict Success if `TcQ_mass` > 15,000, `Treatment_Months` >= 80, and `Histogen_Complex` is either 'Beta', 'Delta', or 'Omicron'.

7. Override condition:
   - If `Histogen_Complex` is 'Omicron' and `TcQ_mass` >= 30,000:
     a. Predict Failure if either Genetic_Class threshold is missed.
     b. Predict Success only if both Genetic_Class threshold values are >= 2 and `Treatment_Months` >= 100.

8. Default to Failure for all cases that do not meet the above criteria explicitly.

### Additional Notes ###
- Apply rules sequentially in priority order as listed.
- Whenever `TcQ_mass` is above a critical threshold (>70,000), scrutinize against more Failure-oriented criteria for conservatism.
- Address ambiguities by leaning towards Failure, but ensure edge scenarios are reviewed thoroughly.