Round 90

Round UUID: a52aca91-0c3e-40f3-917f-7475ddec9df5

Prompt:

Use the following comprehensive and adaptive decision rules to predict success or failure:

1. Complex-Specific Prediction Framework:

Delta Complex Prediction Rules:
- Failure More Likely If:
  * TcQ_mass between 6000 and 20000
  * Treatment_Months < 60 or > 120
  * Genetic_Class_A_Matches ≥ 2
  * Cohort is Melbourne or Delhi (additional risk factor)

- Success Indicators:
  * TcQ_mass > 40000
  * Treatment_Months between 80-150
  * Genetic_Class_A_Matches ≤ 1
  * Male subjects with higher Genetic_Class_B_Matches

Omicron Complex Prediction Rules:
- Failure More Likely If:
  * TcQ_mass between 10000 and 30000
  * Treatment_Months < 75 or > 135
  * Genetic_Class_B_Matches:
    - Females: > 1
    - Males: > 2

- Success Indicators:
  * TcQ_mass > 50000
  * Treatment_Months between 90-180
  * Balanced Genetic_Class_Matches
  * Male subjects with consistent treatment duration

Beta Complex Prediction Rules:
- Failure More Likely If:
  * TcQ_mass between 30000 and 100000
  * Treatment_Months outside 90-180 range
  * Genetic_Class_A_Matches > 2
  * Genetic_Class_B_Matches unbalanced

- Success Indicators:
  * TcQ_mass > 100000
  * Treatment_Months > 120
  * Higher total Genetic_Class_Matches
  * Consistent performance across cohorts

2. Advanced Scoring Mechanism:
- Implement a weighted scoring system considering:
  * Complex-specific TcQ_mass ranges
  * Treatment duration normalized by sex
  * Genetic match quality and balance
  * Subtle cohort performance variations

3. Final Prediction Strategy:
- Calculate cumulative probability score
- Apply probabilistic thresholds
- Consider marginal cases with nuanced scoring
- Prioritize contextual evidence over rigid rules

Make a binary prediction: Success or Failure, based on these comprehensive, context-aware rules.