Round 307

Round UUID: 0a60f936-03a9-4838-bf99-acd86e4806c1

Prompt:

Use the following refined, context-aware decision rules to predict success or failure:

1. Complex-Specific Prediction Framework:

Delta Complex Prediction Rules:
- Failure More Likely If:
  * TcQ_mass:
    - Between 5000-10000: High failure risk
    - Between 10000-25000: Moderate failure risk
    - Penalty if > 50000 without balanced genetic matches
  * Treatment_Months:
    - < 45 or > 105 increases failure probability
    - Sharp decline in success if < 30 or > 120
  * Genetic_Class Interaction:
    - Genetic_Class_A_Matches ≥ 3 AND Genetic_Class_B_Matches > 2
    - Unbalanced genetic match profile
  * Cohort Penalty:
    - Delhi: +20% failure probability
    - Melbourne: +15% failure probability

Omicron Complex Prediction Rules:
- Failure More Likely If:
  * TcQ_mass:
    - Between 8000-35000: Increased failure risk
    - Logarithmic penalty for values outside 20000-60000 range
  * Treatment_Months Stratification:
    - Females: 
      * < 60 or > 150 increases failure risk
    - Males:
      * < 75 or > 180 increases failure risk
  * Genetic_Class_B_Matches Thresholds:
    - Females: > 2 indicates higher failure probability
    - Males: > 3 indicates higher failure probability
  * Complex Interaction: 
    - Total Genetic_Class_Matches > 4 with unbalanced distribution

Beta Complex Prediction Rules:
- Failure More Likely If:
  * TcQ_mass:
    - Between 30000-150000: Moderate failure risk
    - Sharp failure probability increase if > 250000
  * Treatment_Months:
    - Males: Outside 90-210 range
    - Females: Outside 120-240 range
  * Genetic_Class Complexity:
    - Genetic_Class_A_Matches > 2
    - Total Genetic_Class_Matches > 4
    - Highly unbalanced A and B matches
  * Cohort Performance:
    - Delhi: Automatic 10% failure probability increase
    - Consistent underperformance marker

2. Advanced Scoring Mechanism:
- Implement sophisticated multi-factor scoring:
  * Non-linear TcQ_mass normalization
  * Sex-adjusted treatment duration scoring
  * Genetic match quality and balance coefficient
  * Cohort-specific performance modulation
  * Interaction terms between variables

3. Final Prediction Strategy:
- Probabilistic scoring approach
- Contextual evidence weighting
- Marginal case handling with nuanced scoring
- Emphasize complex-specific and sex-specific variations

Make a binary prediction: Success or Failure, based on these comprehensive, adaptive rules.