Round UUID: 474094d6-1f5d-4142-bf07-b6d5362f666a
Prompt:
Use the following refined, context-aware decision rules to predict success or failure:
1. Complex-Specific Prediction Framework:
Delta Complex Prediction Rules:
- Failure More Likely If:
* TcQ_mass between 5000 and 20000
* Treatment_Months < 45 or > 105
* Genetic_Class_A_Matches ≥ 3
* Cohort is Melbourne or Delhi (increased risk)
- Success Indicators:
* TcQ_mass > 45000
* Treatment_Months between 60-135
* Genetic_Class_A_Matches ≤ 2
* Balanced Genetic_Class_Matches (A and B total ≤ 3)
Omicron Complex Prediction Rules:
- Failure More Likely If:
* TcQ_mass between 8000 and 35000
* Treatment_Months < 60 or > 150
* Genetic_Class_B_Matches:
- Females: > 2
- Males: > 3
* Unbalanced genetic match profile
- Success Indicators:
* TcQ_mass > 40000
* Treatment_Months between 90-180
* Total Genetic_Class_Matches between 2-4
* Consistent treatment duration relative to sex
Beta Complex Prediction Rules:
- Failure More Likely If:
* TcQ_mass between 25000 and 150000
* Treatment_Months outside 90-210 range
* Genetic_Class_A_Matches > 2
* Highly unbalanced Genetic_Class_Matches
* Cohort shows consistent underperformance
- Success Indicators:
* TcQ_mass > 100000
* Males: Treatment_Months > 120
* Females: Treatment_Months > 150
* Balanced Genetic_Class_Matches
* Consistent performance across multiple parameters
2. Advanced Scoring Mechanism:
- Implement a weighted, multi-factor scoring system:
* Complex-specific TcQ_mass normalization
* Sex-adjusted treatment duration scoring
* Genetic match quality and balance coefficient
* Cohort performance modulation factor
* Non-linear interaction terms between variables
3. Final Prediction Strategy:
- Calculate comprehensive probability score
- Apply sophisticated probabilistic thresholds
- Emphasize contextual evidence
- Introduce marginal case handling with nuanced scoring
Make a binary prediction: Success or Failure, based on these comprehensive, adaptive rules.